About AllCaN Oesophageal

About AllCaN Oesophageal

What is AllCaN Oesophageal?

The Breakthrough All-Ireland Cancer Network (AllCaN) Oesophageal programme represents a new, focused effort to implement advances in Oesophageal Cancer research as rapidly as possible through the creation of a collaborative, translational cancer research network.

The most talented and promising researchers across Irish institutions will be assembled into an All-Ireland Research Network forming an optimal configuration of expertise needed to solve key problems in Oesophageal Cancer research and positively impact patients in the near future.

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This network will span multiple disciplines and utilise their expertise to address research questions in a coordinated way. The network will have mechanisms for sharing of resources and platforms (knowledge, talent, tools, technologies, etc.) across the team including existing platforms and resources as well as those to be developed, incorporating new methods and technologies into the research groups, and training and networking across the network.

Mechanisms to foster collaborations within and among the network will be employed, an approach that promotes the sharing of information and a goal-oriented focus on measurable milestones of progress. AllCaN Oesophageal will establish the first national network bringing together scientific, clinical and industry teams with decades of collective experience in Barrett’s Oesophagus (BO) and Oesophageal Cancer (OC).

AllCaN Oesophageal will combine interdisciplinary approaches and world-renowned resources to address major health problems on the island of Ireland in Oesophageal Cancer.

By combining data and resources across Ireland, AllCaN Oesophageal will uniquely identify appropriate prevention strategies, lifestyle interventions and novel diagnostic platforms and therapeutics through enhanced understanding of the BO-OAC progression. Importantly, early detection will lead to better survival outcomes for patients.

AllCaN Oesophageal propose research projects to:

About AllCaN Oesophageal

Who is leading AllCaN Oesophageal?

AllCaN Oesophageal Team Leader

Professor Jacintha O’Sullivan

Professor in Translational Oncology and Education Director for the Trinity St. James’s Cancer Institute, Department of Surgery, Trinity College Dublin

AllCaN Oesophageal Team Co-Leader

Professor Helen Coleman

Professor of Cancer Epidemiology and Deputy Director of the Northern Ireland Cancer Registry, Centre for Public Health, Queens University Belfast

AllCaN Oesophageal Team Co-Leader

Professor Juliette Hussey

Professor of Cancer Rehabilitation and Survivorship, Discipline of Physiotherapy, Trinity College Dublin

AllCaN Oesophageal Programme Manager

Dr James Phelan

Department of Surgery, Trinity College Dublin

AllCaN Oesophageal will maximise the training of research leaders through blending skills in:

Specifically, by monitoring the number of patients with BO and OC across the island of Ireland, AllCaN Oesophageal will examine for the first-time if potential inequalities exist across demographics, healthcare systems and patient outcomes and how lifestyle factors and medications influence reflux symptoms and progression.

Lifestyle interventions will be tailored to reduce symptoms and improve quality of life (including mental health and wellbeing). In collaboration with industry, the biomarker and therapeutic programmes will accelerate translation of relevant diagnostic and prognostic discoveries into clinical practice.

We will provide excellent opportunities for early career trainees within a structured programme, linked with industry partners, mobility research secondments and patient involvement. The outputs of AllCaN Oesophageal will significantly improve the management and outcomes for BO and OC patients.

AllCaN Oesophageal

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